Programme
François Jacob Conference:
Evolution, Structure and Function of
Chromosomes High Order Structure
Paris, June 4-7, 2019
 
Tuesday, June 4, 2019
Opening of the meeting, Introduction
14:30 pm-15:00 pm
Session I Genome Evolution
15:00 pm-17:40 pm
0
15:00 pm

Xenopus Genome

D. Rokhsar
UC Berkeley, Berkeley, Etats-Unis 
0
15:30 pm

Evolution of Vertebrate Genome Biology: Eons and Embryogenesis

J. Smith
Univ. of Kentuky, Lexington, Etats-Unis 
0
16:00 pm

Coffee Break


0
16:30 pm

Diversification of genome structure/function relationships in metazoans

H. Marlow
Dept of Developmental& stem cell biology, Institut Pasteur, Paris, France 
0
17:00 pm

Two short talks


Cocktail reception
17:45 pm-20:00 pm
Wednesday, June 5, 2019
Session II Genome organisation during development and differentiation
09:00 am-16:30 pm
Chair: Tajbakhsh Shahragim,
0
09:00 am

Chromatin architecture and the Hox clock

D. Duboule
University of Geneva, Geneva, Suisse 
0
09:30 am

Dynamic folding of the X chromosome and its relationship with gene silencing during X inactivation

E. Heard
Mammalian Developmental Epigenetics Group, Institut Curie, Paris, France 
0
10:00 am

Two short talks


0
10:40 am

Coffee Break


0
11:10 am

Spatial chromatin reorganization during zygotic reprogramming to totipotency

K. Tachibana-Konwalski
IMB, Vienna, Autriche 
0
11:40 am

Two short talks


0
12:20 pm

Lunch


0
14:00 pm

Dynamic chromatin architecture in early mammalian development

W. Xie
Tsinghua Univ, Beijing, Chine 
0
14:30 pm

In situ genome architecture of neuronal subtypes

A. Pombo
MDC, Berlin, Allemagne 
0
15:00 pm

Three short talks


0
16:00 pm

Chromatin and chromosome dynamics at DNA double strand breaks

G. Legube
CBI, Toulouse, France 
Poster session with cheese and wine
16:00 pm-20:00 pm
Thursday, June 6, 2019
Session III Genome expression
09:00 am-12:20 pm
0
09:00 am

3D genome folding and Polycomb proteins in development and epigenetic inheritance

G. Cavalli
IGH, Montpellier, France 
0
09:30 am

Enhancer-promoter interactions during Drosophila embryogenesis

Y. Ghavi-Helm
ENS, Lyon, France 
0
10:00 am

Coffee break


0
10:30 am

Three short talks


0
11:30 am

Chromosome dynamics control early developmental decisions

P. Fraser
The Barbraham Institute, Cambridge, Royaume-Uni 
0
12:00 pm

Short talk


Lunch
12:20 pm-14:00 pm
Session IV Cell Cycle and division
14:00 pm-18:00 pm
0
14:00 pm

Chromosomes, cohesin, and cohesion

K. Nasmyth
University of Oxford, Oxford, Royaume-Uni 
0
14:30 pm

New insights into vertebrate mitotic chromosome structure and formation

W. Earnshaw
University of Edinburgh, Edinburgh, Royaume-Uni 
0
15:00 pm

Chromosomes as mechanical objects

N. Kleckner
Dept. of Molecular & Cellular Biology, Harvard University, Cambridge, Etats-Unis 
0
15:30 pm

Two short talks


0
16:10 pm

Coffee break


0
16:40 pm

Towards the recombination-independent mechanism of homologous DNA-DNA pairing

E. Gladyshev
Institut Pasteur, Paris, France 
0
17:10 pm

Regulation of budding yeast chromosome folding during mitosis

R. Koszul
Dept. of Genomes & Genetics, Institut Pasteur, Paris, France 
0
17:40 pm

Short talk


Visit of the Orsay museum
18:30 pm-20:00 pm
Banquet dinner - Orsay Museum
20:00 pm-23:00 pm
Friday, June 7, 2019
Session V Genomes and disease
09:00 am-12:40 pm
0
09:00 am

Nuclear architecture and therapeutic opportunities in hematopoietic cells

G. Blobel
UPenn, Philadelphia, Etats-Unis 
0
09:30 am

Function and regulation of the 3D folding of the genome

F. Spitz
Developmental & Stem Cell Biology Dept., Institut Pasteur, Paris, France 
0
10:00 am

Coffee break


0
10:30 am

Three short talks


0
11:30 am

3D Epigenome reconfiguration in brain development and disease

J. Philips-Cremins
UPenn, Philadelphia, Etats-Unis 
0
12:00 pm

Two short talks


Lunch
12:40 pm-14:10 pm
Session VI Imaging and physical basis of chromosome structure and function
14:10 pm-17:40 pm
0
14:40 pm

Compact organization of chromatin domains in living cells

K. Maeshima
Nat. Inst. of Genetic, Japon 
0
15:10 pm

A solid state conceptualization of information transfer from gene to message to protein

S. Mcknight
UTSouthwestern, Dallas, Etats-Unis 
0
15:40 pm

Revealing eukaryotic chromosome organization and function using advanced microscopies

M. Nollman
CBS, Montpellier, France 
0
16:10 pm

Coffee Break


0
16:40 pm

Epigenetics, morphology, mechanics and function of the mammalian cell nucleus

J. Marko
Northwestern University, Evanston, Etats-Unis 
0
17:10 pm

Imaging enhancer dynamics in living fly embryos

T. Gregor
Institut Pasteur, Paris, France 
Summary and Conclusions
17:40 pm-18:00 pm

 

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